- Anomalies of uterus
- Hormone Replacement Therapy
- Induction of Ovulation
- Male Infertility
- Menstrual Irregularities
- Ovarian Cysts
- Premature Menopause
- Premature Ovarian Failure (POF)
- Removal of fibroids
- Semen Analysis
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How It Works
Gonadotropin fertility medicines contain follicle-stimulating hormone (FSH), luteinizing hormone (LH), or both. These hormones play a central role in egg production.
Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are needed for egg production. Early in the menstrual cycle, a woman with low hormone levels who is not ovulating can have daily human menopausal gonadotropin (hMG) or recombinant human FSH (rFSH) injections for an average of 12 days. If this helps develop mature follicles, the ovary is ready to ovulate. One dose of human chorionic gonadotropin (hCG) is then used to stimulate ovulation.
Why It Is Used
Gonadotropins may be used:
- To stimulate ovulation related to low natural gonadotropin or estrogen levels. (This is most commonly seen in women with excessive exercise or eating disorders.)
- When clomiphene alone or clomiphene combined with another medicine has been ineffective for correcting irregular or no ovulation caused by polycyscic ovary syndrome (PCOS).
- For developing multiple egg follicles on the ovaries. Multiple eggs are harvested and used in assisted reproductive techniques such as in vitro fertilization or gamete intrafallopian transfer.
- In combination with intrauterine insemination for couples with unexplained infertility when clomiphene has not worked.
The combination human menopausal gonadotropin (hMG)/human chorionic gonadotropin (hCG) or recombinant human follicle-stimulating hormone (rFSH)/hCG treatment can consistently stimulate ovulation. It results in pregnancy in 60 out of 100 women failing to ovulate. But of those pregnancies, up to 35% end in miscarriage.
All medicines have side effects. But many people don’t feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
- Usually the benefits of the medicine are more important than any minor side effects.
- Side effects may go away after you take the medicine for a while.
- If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Do not suddenly quit taking your medicine unless your doctor tells you to.